ANTIMICROBIAL PROPERTIES OF ACETYLENE QUATERNARY AMMONIUM SALTS

For a long period of time, saturated quaternary ammonium salts have been used as components compositions that antimicrobial properties against certain strains microorganisms. The disadvantage using such is the formation resistance some microorganisms to latter. Thus, it seems relevant create based on with which had no contact in environment. This article presents results experimental studies activity synthesized acetylenic salts, tertiary amines, well commercially available relation test cultures Proteus mirabilis , vulgaris Salmonella typhimurium Pseudomonas aeruginosa Escherichia coli Shigella sonne Serratia marcescens Staphylococcus aureus Candida albicans Saccharomyces cerevisiae Penicillium spp . and Bacillus cereus diameter zones inhibition growth by test-cultures was determined disk-diffusion method. action solutions various concentrations carried out method serial dilutions. minimum inhibitory concentration has determined. research showed range tri-n-octylprop-2-ynylammonium bromide for studied from 0.1 0.0001%, bromides tri-n-octylbut-2-ynyl- tri-n-octyloct -2-ynylammonium - 1 while limiting exhibit an effect similar pathogenic at order magnitude higher more. can be promising agents.